2011 Fiscal Year Final Research Report
Role of IL-18 in diabetes mellitus.
| Project/Area Number |
22790535
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Laboratory medicine
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| Research Institution | Hyogo Medical University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Keywords | 臨床化学 / 糖尿病 |
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| Research Abstract |
The purpose of this study was to investigate the relationship between oxidative stress and cytokines in diabetes mellitus and find the disease-specific marker. It was revealed that the reactive oxygen species(ROS), including hydrogen peroxide, nitric oxide and peroxynitrite, enhanced the nitric oxide production via the expression of interferon beta. This mechanism may be involved in the development of diabetes.
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