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2012 Fiscal Year Final Research Report

The association between BNP level, NPPB genotype and CVD risk in general Japanese population.

Research Project

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Project/Area Number 22790544
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Hygiene
Research InstitutionShiga University of Medical Science

Principal Investigator

TAKASHIMA Naoyuki  滋賀医科大学, 医学部, 特任助教 (80435883)

Project Period (FY) 2010 – 2012
KeywordsNPPB遺伝子多型 / 脳性ナトリウム利尿ペプチド / 左室肥大 / 循環器疾患発症
Research Abstract

Brain natriuretic peptide (BNP) is a clinical useful marker forheart failure. In the present study, we observed the significant association between plasma BNP levels and electrocardiographic left ventricular hypertrophy. However, we did not find the significant association between electrocardiographic left ventricular hypertrophy and the NPPB genotype. Furthermore, we did not find any significant association between the NPPB genotype and future cardiovascular disease risk. Therefore, it is needed for further research to examine the association between CVD risk and the NPPB genotype.

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Published: 2014-08-29  

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