2011 Fiscal Year Final Research Report
Influence of Perfluorinated Chemicals on the health of future generation
| Project/Area Number |
22790568
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Public health/Health science
|
|---|
| Research Institution | Hokkaido Bunkyo University |
|---|
Principal Investigator |
KASHINO Ikuko 北海道文教大学, 人間科学部・健康栄養学科, 助手 (20515936)
|
|---|
| Project Period (FY) |
2010 – 2011
|
| Keywords | 有機フッ素化合物 / 環境 / 社会医学 / 測定法 |
|---|
| Research Abstract |
Main goal of our study was to investigate the correlation between exposure to PFCs, perfluorinated chemicals, of dairy life level in maternal blood and physical child development. During study period, first, we developed a method of PFCs measurement in blood with Ultra performance liquid Chromatography and tandem mass spectrometry, through modifying preprocessing of PFCs in blood, which allowed us to analyze 13 types of perfluorinated chemicals in short time with high precision. Second, our results showed significantly lower concentration of PFOS/PFOA/PFTrDA of pregnant women in Hokkaido than that of women of childbearing age in Japan and other countries. Third, the results showed level of PFCs had decreased from 2003 to 2011. Fourth, of 8, 426 participated women from 2003 to 2005, percentages of Small-for-gestational-age and congenital anomalies were 7. 62% and 1. 48%, respectively. Those percentages were slightly lower than the percentages reported in monitoring congenital anomalies by Japanese Association of Obstetricians and Gynecologists.
|
Research Products
(11 results)
-
[Journal Article] Effects of Maternal 5, 10-Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms and Tobacco Smoking on Infant Birth Weight in a Japanese Population2011
Author(s)
Yila TA, Sasaki S, Miyashita C, Braimoh TS, Kashino I, Kobayashi S, Okada E, Baba T, Yoshioka E, Minakami H, Endo G, Sengoku K, Kishi R
-
Journal Title
-
-
-
[Presentation] Effects of prenatal environmental tobacco smoke exposure on infant birth size2011
Author(s)
Braimoh T, Sasaki S, Yila TA, Baba T, Miyashita C, Okada E, Kashino I, Ito K, Kobayashi S, Yoshioka E, Kishi R
Organizer
The American Public Health Association(APHA) 139th Annual Meeting and Exposition Washington
Place of Presentation
DC, USA
Year and Date
20111029-1102
-
-
-
-
-
[Presentation] Prenatal Exposure to Dioxins in Relation to Allergy and Infection in Infancy-Hokkaido Study on Environment and Chidren's Health-2010
Author(s)
Miyashita C, Sasaki S, Yoshioka E, Yila TA, Baba T, Braimoh T, Kashino I, Okada E, Kobayashi S, Otake Y, Limpar M, Kajiwara J, Todaka T, Kishi R
Organizer
ISES-ISEE 2010 : Joint Conference of International Society of Exposure Science & International Society for Environment Epidemiology Seoul
Place of Presentation
Korea
Year and Date
20100828-0901
-
-
