2012 Fiscal Year Final Research Report
Pathophysiological analysis and clinical application of oligosaccharide alterations in inflammatory bowel disease
| Project/Area Number |
22790643
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Gastroenterology
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Keywords | 下部消化管学(小腸、大腸) |
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| Research Abstract |
Focused on the increase in agalactosyl IgG in patients with inflammatory bowel disease (IBD), the pathophysiological roles of oligosaccharide alterations on immunoglobulin and immune cells were investigated using colitis model. For clinical application, the relationship between oligosaccharide alterations and patient characteristics in IBD patients were also clarified.
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