2011 Fiscal Year Final Research Report
Cardiac sympathetic nervous function in patients with atrial fibrillation
| Project/Area Number |
22790683
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Yamagata University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Keywords | 心房細動 / 心筋焼灼術 / 心臓交感神経 |
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| Research Abstract |
The ^<123>I-MIBG scintigraphy demonstrated an enhanced adrenergic nervous function (high washout rate) and decreased adrenergic nervous distribution (low heart to mediastinum ratios) in patients with both paroxysmal and persistent AF. Only the ^<123>I-MIBG washout rate was a multivariate predictor of an AF recurrence (hazard ratio : 1.6, 95% confidence interval : 1.004-1.125, P = 0.037).
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