2011 Fiscal Year Final Research Report

Analysis of roles and physiological functions of Intrinsic Cardiac Adrenergic Cell in rodent cardiac transplantation model.

Research Project

Project/Area Number	22790727
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Circulatory organs internal medicine
Research Institution	Keio University
Principal Investigator	TAMURA Yuichi 慶應義塾大学, 医学部, 特任助教 (00468498)
Project Period (FY)	2010 – 2011
Keywords	分子心臓病態学
Research Abstract	We identified the Intrinsic Cardiac Adrenergic Cell(ICA cell) are derived from neural crest by analyzing P0-Cre x Floxed-GFP transgenic mice. We found a driving factor for promoting the proliferation and differentiation into ICA cell. And we confirmed the contraction and heart rate of transplanted hearts were affected with the development of ICA cell.