2011 Fiscal Year Final Research Report
Exploring the mechanism of the glomerular parietal epithelial cell proliferation in crescentic glomerulonephritis and its treatment
| Project/Area Number |
22790779
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Kidney internal medicine
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| Research Institution | The University of Tokyo |
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Principal Investigator |
OHSE Takamoto 東京大学, 医学部附属病院, 助教 (10568447)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 糸球体壁細胞 / 半月体形成性腎炎 / 細胞増殖 |
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| Research Abstract |
It was revealed that the proliferation of glomerular parietal epithelial cells was induced by collagen. The mechanistic study for this collagen induced proliferation is now being investigated with in vitro and in vivo(anti-GBM nephritis mouse model) models.
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