2011 Fiscal Year Final Research Report
The role of Notch signaling in megakaryocytopoiesis
| Project/Area Number |
22790896
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Hematology
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Keywords | 血栓 / 止血学 |
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| Research Abstract |
To clarify the precise differentiation pathway of megakaryocyte lineage from hematopoietic stem cell and the role of Notch signaling during megakaryocytopoiesis, we identified a new class of megakaryocyte progenitors in the adult mouse bone marrow and demonstrated the gene expression pattern (including Notch signal molecules).
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