2012 Fiscal Year Final Research Report
Analysis for the role of autophagy in food allergy
| Project/Area Number |
22790970
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Pediatrics
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| Research Institution | University of Fukui |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Keywords | 食物アレルギー / オートファジー / 免疫学 / 経口免疫寛容 |
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| Research Abstract |
Autophagy may have a role in allergic immune responses. We sought to test the hypothesis that modulation of autophagy affects provocation of anaphylaxis on oral allergen challenge. It is suggested that the modulation of autophagy ameliorates IgE-mediated anaphylaxis on oral allergen challenge in food allergic mouse model.
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