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2012 Fiscal Year Final Research Report

Basic investigation for treatment of chronic lung disease by G-CSF administration mobilizing of the stem cell to peripheral blood

Research Project

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Project/Area Number 22791037
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Embryonic/Neonatal medicine
Research InstitutionKeio University

Principal Investigator

HOKUTO Isamu  慶應義塾大学, 医学部, 助教 (00296625)

Project Period (FY) 2010 – 2012
Keywords再生医学 / サイトカイン
Research Abstract

G-CSF administration significantly improved a mouse model of chronic lung disease. It is unclear whether G-CSF-mobilized peripheral blood stem cells differentiated into pulmonary epithelial cells, whether G-CSF induced the proliferation and differentiatio

  • Research Products

    (15 results)

All 2012 2011 2010

All Journal Article (8 results) (of which Peer Reviewed: 8 results) Presentation (7 results)

  • [Journal Article] Metabolic acidosis due to continuous drainage of massive chylous pleural effusion in two neonates2012

    • Author(s)
      Okishio E, Arimitsu T, Miwa M,Matsuzaki Y, Hokuto I, Ikeda K
    • Journal Title

      Pediatr Int

      Volume: 54(5) Pages: 732-3

    • Peer Reviewed
  • [Journal Article] Hepatocyte growth factor levels of cord blood in healthy term newborns.2012

    • Author(s)
      Hokuto I, Matsuzaki Y, Miwa M, ArimitsuT, Okishio E, Ikeda K
    • Journal Title

      Arch Dis Child Fetal Neonatal Ed.

      Volume: 97(5) Pages: F389

    • Peer Reviewed
  • [Journal Article] Surfactant protein A in gastric fluid at birth as a useful marker of differentiation diagnosis between respiratory distress syndrome and transient tachypnea of the newborn2011

    • Author(s)
      Matsuzaki Y, Hokuto I, Ikeda K
    • Journal Title

      Pediatr Int

      Volume: 53(5) Pages: 788-9

    • Peer Reviewed
  • [Journal Article] Functional hemispheric specialization in processing phonemic and prosodic auditory changes in neonates2011

    • Author(s)
      Arimitsu T, Uchida-Ota M, Yagihashi T, Kojima S, Watanabe S, Hokuto I, Ikeda K, Takahashi T, Minagawa-Kawai Y
    • Journal Title

      Front Psychol

      Volume: 2 Pages: 202

    • Peer Reviewed
  • [Journal Article] Usefulness of measurement of urinary N-terminal pro-brain natriuretic peptide in neonatal period2011

    • Author(s)
      Kurihara N, Miwa M, Matsuzaki Y, Hokuto I, Kikuchi H, Katano S, Ikeda K
    • Journal Title

      Pediatr Int

      Volume: 53(4) Pages: 608

    • Peer Reviewed
  • [Journal Article] Final diagnosis in patients with congenital cystic lung disease detected by fetal ultrasonography2011

    • Author(s)
      Kuratsuji G, Hokuto I, Higuchi M, Koinuma G, Morikawa Y, Hoshino K, Tanaka M, Miyakoshi K, Ikeda K
    • Journal Title

      Pediatr Int

      Volume: 53(1) Pages: 131-2

    • Peer Reviewed
  • [Journal Article] Survival of a congenital ileal atresia infant weighing 359 g at birth after laparotomy2011

    • Author(s)
      Fuchimoto Y, Tomita H, Takasato F, Yamamoto Y, Mori M, Shimojima N, Hoshino K, Hokuto I, Ikeda K, Morikawa Y
    • Journal Title

      Pediatr Int

      Volume: 53(1) Pages: 127-8

    • Peer Reviewed
  • [Journal Article] C-reactive protein in extremely low birth weight infants using evanescent wave immunoassay to make normative standards after birth2010

    • Author(s)
      Furukawa R, Miwa M, Hokuto I, Ikeda K
    • Journal Title

      Pediatr Int

      Volume: 52(6) Pages: 898

    • Peer Reviewed
  • [Presentation] distressの無い状態で出生した正期産児の臍帯血血清HGF値2012

    • Author(s)
      北東功,松崎陽平, 有光威志, 三輪雅之, 木下眞里, 池田一成
    • Organizer
      第57回日本未熟児新生児学会
    • Place of Presentation
      熊本
    • Year and Date
      2012-11-27
  • [Presentation] G-CSF administration improves chronic lung disease caused by exposure tohigh-concentration oxygen in neonatal mice2012

    • Author(s)
      Isamu Hokuto, Takeshi Arimitsu, Yohei Matsuzaki, Kazushige Ikeda
    • Place of Presentation
      ウィーン、オーストリア
    • Year and Date
      2012-09-05
  • [Presentation] 高濃度酸素投与による慢性肺疾患モデルマウスに対するG‐CSF投与は有効か-第2報-2012

    • Author(s)
      北東功, 松崎陽平, 有光威志, 三輪雅之, 池田一成
    • Organizer
      第48回日本周産期・新生児医学会総会
    • Place of Presentation
      大宮
    • Year and Date
      2012-07-09
  • [Presentation] 当院における出生体重400g未満の児へのカルシウムとリンの補給2011

    • Author(s)
      北東功, 松崎陽平, 三輪雅之, 有光威志, 置塩英美, 本間英和, 池田一成
    • Organizer
      第56回日本未熟児新生児医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-13
  • [Presentation] Association between severe bronchopulmonary dysplasia and serum HGF levels in premature infants during early postnatal life2011

    • Author(s)
      Isamu Hokuto, Takeshi Arimitsu,Masayuki Miwa, Yohei Matsuzaki,Kazushige Ikeda
    • Organizer
      European respiratory society annual congress
    • Place of Presentation
      アムステルダム、オランダ
    • Year and Date
      2011-09-27
  • [Presentation] 高濃度酸素投与による慢性肺疾患モデルマウスに対するG-CSF 投与は有効か?2011

    • Author(s)
      北東功, 有光威志, 松崎陽平, 三輪雅之, 置塩英美, 池田一成
    • Organizer
      第47回日本周産期・新生児医学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2011-07-11
  • [Presentation] 血清HGF は慢性肺疾患の重症度予測因子となりうるか?2010

    • Author(s)
      北東功, 三輪雅之, 松崎陽平, 有光威志, 置塩英美, 池田一成
    • Organizer
      第55回日本未熟児新生児学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-11-06

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Published: 2014-08-29  

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