2011 Fiscal Year Final Research Report
A study on the pathophysiology of pervasive developmental disorder and development of diagnostic support tool from a viewpoint of gender difference
| Project/Area Number |
22791133
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Psychiatric science
|
|---|
| Research Institution | Sapporo Medical University |
|---|
Principal Investigator |
TATENO Masaru 札幌医科大学, 医学部, 講師 (60464492)
|
|---|
| Project Period (FY) |
2010 – 2011
|
| Keywords | 児童思春期精神医学 |
|---|
| Research Abstract |
The Prisoner's Dilemma illustrates the paradoxical disposition of interaction between two individuals with opposing interests. We investigated the cognitive characteristics of Pervasive Developmental Disorder(PDD) by using a game based on this dilemma and demonstrated that the subjects with PDD had lower awareness to the others compared to the controls. Prenatal exposure to high dose ethanol causes various sequelae in the child including decreased social interaction. We performed transvenous transplantation of neural stem cells to the Fetal Alcohol Spectrum Disorders model rat and observed the improvement of the results of social interaction test. These results suggest that repair of neural network damage could be related to clinical symptoms in PDD.
|
