2012 Fiscal Year Final Research Report
The research of neuroimaging in HIV-positive
| Project/Area Number |
22791145
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Psychiatric science
|
|---|
| Research Institution | Nippon Medical School |
|---|
Principal Investigator |
ITO Shigeo 日本医科大学, 医学部, 助教 (90515975)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Keywords | 脳機能画像 / HIV |
|---|
| Research Abstract |
We performed the research of neuropsychological test and brain MRI(magnetic resonance imaging） in HIV（human immunodeficiency virus）-positive who have no psychiatric and neurological symptoms and healthy subjects. The MRI study of brain volume was used by the VBM (Voxel-Based-Morphometry) method. Without differences between the two groups in screening tests, HIV-positive group was decreased executive function, behavioral activation system and mood modulation in detailed neuropsychological tests. There were no significant difference at the gray matter and the white matter, compared between groups of the brain volumes in MRI, but the findings suspected by neuronal-degeneration causing to HIV may become an indicator of the AIDS（acquiredimmunodeficiency syndrome）.
|
