2012 Fiscal Year Final Research Report
Transport Response in mammalian young: Analysis of neuromolecular mechanism
Project/Area Number |
22791153
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Psychiatric science
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Research Institution | The Institute of Physical and Chemical Research |
Principal Investigator |
YOSHIDA Sachine 独立行政法人理化学研究所, 黒田研究ユニット, 研究員 (90513458)
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Project Period (FY) |
2010 – 2012
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Keywords | マウス / 輸送反応 / 生後発達 / 親子関係 |
Research Abstract |
A mother carries the young in many altricial mammals. Meanwhile, the transported young immediately assume a compact posture and stay calm. This young's response to maternal transport is called "Transport Response (TR)". We studied the postnatal development and regulatory mechanisms of TR using mouse pups. We found that TR was an intricate combination of immobilization and postural regulation. Tactile sensation and proprioception were essential for immobilization component of TR. The postural regulation component of TR was dependent on the cerebellar function. These findings indicate that TR is a filial-specific response that involves multiple brain areas for its regulation.
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[Journal Article] Infant calming responses during maternal carrying in humans and mice
Author(s)
Esposito G#, Yoshida S#, Ohnishi R, Tsuneoka Y, Rostango M,Yokota S, Okabe S, Kamiya K, Hoshino M, Shimizu M, Venuti P, Kikusui T, Kato T, Kuroda KO
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Journal Title
Current Biol
Volume: (Accepted)
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