2011 Fiscal Year Final Research Report
Optimization and standardization of longitudinal brain image analysis for dementia
| Project/Area Number |
22791165
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Radiation science
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Keywords | Alzheimer病 / 脳画像解析 / 縦断的評価 / Positron Emission Tomography |
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| Research Abstract |
The aim of this study was to optimize and standardize the analysis method for the longitudinal brain image evaluation for dementia. Neurostat program was used for 3D-SSP analyses. As the index for the evaluation, A)posterior cingulate cortex (PCC), and B)PCC+ parietal and tempotal lobes showed relatively small sample size for the detection of the changes over time. However, these values seem to be large for the clinical trials of the new drugs for Alzheimer's disease. Further investigation is required.
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