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2011 Fiscal Year Final Research Report

Dose calculation system using in-treatment cone-beam CT for adaptive radiation therapy

Research Project

  • PDF
Project/Area Number 22791176
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Radiation science
Research InstitutionThe University of Tokyo

Principal Investigator

HAGA Akihiro  東京大学, 医学部附属病院, 助教 (30448021)

Project Period (FY) 2010 – 2011
Keywords強度変調放射線治療 / VMAT / コーンビームCT / Deformable registration / 高精度放射線治療 / 経時的最適化 / Adaptive radiotherapy / 臓器の動き
Research Abstract

In this research, I developed a four dimensional(4D) cone-beam CT(CBCT) during course of treatment and during treatment by using linac-mounted diagnostic kV X-ray, which corresponds to time-dependent variation of the irradiated cites. With the 4D CBCT, I established the system to verify a cumulative dose distribution in a patient by introducing non-rigid registration(deformable image registration). Through this study, the method to estimate an irradiation accompanied by CBCT imaging and the image processing automation were developed.

  • Research Products

    (27 results)

All 2012 2011 2010 Other

All Journal Article (14 results) (of which Peer Reviewed: 14 results) Presentation (9 results) Book (3 results) Remarks (1 results)

  • [Journal Article] Single-Arc Volumetric Modulated Arc Therapy Planning for Left Breast Cancer and Regional Nodes2012

    • Author(s)
      A. Sakumi, K. Shiraishi, T. Onoe, K. Yamamoto, A. Haga, et al.
    • Journal Title

      J. Radiat. Res. 2

      Volume: 53(1) Pages: 151-3

    • Peer Reviewed
  • [Journal Article] Correlation between bladder volume and irradiated dose of small bowel in CT-based planning of intracavitary brachytherapy for cervical cancer2012

    • Author(s)
      H. Yamashita, K Nakagawa, K. Okuma, A. Sakumi, A. Haga, et al.
    • Journal Title

      Jpn. J. Clin. Oncol

    • Peer Reviewed
  • [Journal Article] 4D-CBCT reconstruction using MV portal imaging during volumetric modulatedarc therapy2011

    • Author(s)
      S. Kida, et al.
    • Journal Title

      Radiotherapy and Oncology 100

      Pages: 380-385

    • Peer Reviewed
  • [Journal Article] 呼気および吸気時CT画像に基づく胸郭運動モデルの構築2011

    • Author(s)
      伊藤広貴、越塚誠一、芳賀昭弘、中川恵一
    • Journal Title

      Medical Imaging Technology

      Volume: Vol.29, No.4 Pages: 208-214

    • Peer Reviewed
  • [Journal Article] 320列CT装置を用いた肺定位放射線治療における標的の軌跡解析2011

    • Author(s)
      今江禄一, 芳賀昭弘, 中川恵一, 他
    • Journal Title

      日本放射線技術学会

      Volume: 67(3) Pages: 202-211

    • Peer Reviewed
  • [Journal Article] First In-situ Dose Calculation Report Using In-treatment Kilovoltage Cone-beam CT and In-treatment Linac Parameters during Volumetric Modulated Arc Therapy2011

    • Author(s)
      A. Sakumi, A. Haga, et al.
    • Journal Title

      Journal of Radiation Research

      Volume: 52 Pages: 536-537

    • Peer Reviewed
  • [Journal Article] Cone Beam Computed Tomography Data Acquisition during VMAT Delivery with Subsequent Respiratory Phase Sorting Based on Projection Image Cross-correlation2011

    • Author(s)
      K. Nakagawa, S. Kida, A. Haga, et al.
    • Journal Title

      Journal of Radiation Research

      Volume: 52 Pages: 112-113

    • Peer Reviewed
  • [Journal Article] Four-Dimensional Measurement of the Displacement of Internal Fiducial Markers During 320-Multislice Computed Tomography Scanning of Thoracic Esophageal Cancer2011

    • Author(s)
      H. Yamashita, S. Kida, A. Sakumi, A. Haga, et al.
    • Journal Title

      International Journal of Radiation Oncology Biology Physics

      Volume: Vol.79 Pages: 588-595

    • Peer Reviewed
  • [Journal Article] Prescreening based on the presence of CT-scan abnormalities and biomarkers(KL-6 and SP-D) may reduce severe radiation pneumonitis after stereotactic radiotherapy2010

    • Author(s)
      H. Yamashita, K. S. Shibata, A. Okuma, A. Haga, et al.
    • Journal Title

      Radiation and Oncology 2010 May 9

      Volume: 5(1) Pages: 32

    • Peer Reviewed
  • [Journal Article] 放射線治療のための粒子法シミュレーションに基づく胸部Simulation-based4DCTの構成2010

    • Author(s)
      伊藤広貴, 越塚誠一, 志野亮作, 芳賀昭弘, 他
    • Journal Title

      Medical Imaging Technology

      Volume: Vol.28, No.4 Pages: 229-236

    • Peer Reviewed
  • [Journal Article] 胸式呼吸と心拍動による肺野変形のAxial面における粒子法シミュレーション2010

    • Author(s)
      伊藤広貴, 越塚誠一, 中川恵一, 芳賀昭弘
    • Journal Title

      日本シミュレーション学会論文誌

      Volume: Vol.2, No.3 Pages: 93-10

    • Peer Reviewed
  • [Journal Article] Patient setup error and day-to-day esophageal motion error analyzed by cone-beam computed tomography in radiation therapy2010

    • Author(s)
      H. Yamashita, A. Haga, et al.
    • Journal Title

      Acta Oncologica

      Volume: 49 Pages: 485-409

    • Peer Reviewed
  • [Journal Article] In-treatment 4D cone-beam CT withimage-based respiratory phase recognition

    • Author(s)
      S. Kida, et al.
    • Journal Title

      Radiological Physics and Technology, to be published

    • DOI

      DOI:10.1007s12194-012-0146-73

    • Peer Reviewed
  • [Journal Article] Four-dimensional measurement of thedisplacement of internal fiducial and skinmarkers during 320-multislice computed tomography scanning of breast cancer

    • Author(s)
      H. Yamashita, K. Ohkuma, K. Tada, K. Shiraishi, W. Takahashi, S. Shibata, A. Sakumi, N. Saotome, A. Haga, et al.
    • Journal Title

      International Journal of Radiation Oncology, Biology, to be published

    • Peer Reviewed
  • [Presentation] Four Dimensional Cone-Beam CT and VMAT2012

    • Author(s)
      A. Haga
    • Organizer
      Second International Conference on Real-time Tumor-tracking Radiation Therapy with 4D Molecular Imaging Technique
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2012-02-17
  • [Presentation] Lung SBRT using VMAT and in-treatment KV & MV cone beam CT imaging2012

    • Author(s)
      A. Haga.
    • Organizer
      Symposium for Stereotactic Body Radiation Therapy(SBRT) for Liver, Lung & SpineTumour
    • Place of Presentation
      New Delhi, India
    • Year and Date
      2012-01-30
  • [Presentation] Novel verification method using in-treatment 4D CBCT2011

    • Author(s)
      A. Haga, S. Kida, N. Saotome, et al.
    • Organizer
      The 6th JKMP and the 11th AOCMP Meeting
    • Place of Presentation
      Fukuoka, Japan
    • Year and Date
      2011-10-01
  • [Presentation] 強度変調放射線治療の品質管理2011

    • Author(s)
      芳賀昭弘
    • Organizer
      日本医学物理学会品質管理講習会
    • Place of Presentation
      福岡
    • Year and Date
      2011-09-27
  • [Presentation] VMAT with MONACO2011

    • Author(s)
      A. Haga, et al.
    • Organizer
      the novel TPS : Present status and future application. ESTRO2011
    • Place of Presentation
      London, England
    • Year and Date
      2011-05-09
  • [Presentation] 放射線治療の高精度化が臨床に与える影響2010

    • Author(s)
      芳賀昭弘
    • Organizer
      Joint Symposium in JASTRO meeting
    • Place of Presentation
      舞浜,千葉
    • Year and Date
      2010-11-15
  • [Presentation] 最新X線治療~経時的最適化放射線治療2010

    • Author(s)
      芳賀昭弘
    • Organizer
      放射線によるがん治療・診断の最前線を探る(シンポジウム)
    • Place of Presentation
      東京
    • Year and Date
      2010-10-27
  • [Presentation] Tracking Volume Change during IMRT treatment using non-rigid registration2010

    • Author(s)
      A. Haga, et al.
    • Organizer
      ESTRO2010
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2010-09-06
  • [Presentation] Comparison of treatment planning systems in Elekta Volumetric Modulated Arc Therapy(Elekta VMAT)-prostate cancer study2010

    • Author(s)
      A. Haga, et al.
    • Organizer
      AAPM2010
    • Place of Presentation
      Philadelphia, America
    • Year and Date
      2010-08-01
  • [Book] 病院と患者のための放射線治療2012

    • Author(s)
      中川恵一、芳賀昭弘, 他
    • Total Pages
      23-28, 134-137, 139
    • Publisher
      産業科学株式会社
  • [Book] 放射線治療最前線2011

    • Author(s)
      中川恵一、芳賀昭弘, 他多数
    • Total Pages
      6-7, 46-48
    • Publisher
      インナービジョン
  • [Book] 放射線治療と医学物理の理工学

    • Author(s)
      芳賀昭弘, 他多数
    • Publisher
      養賢堂
  • [Remarks]

    • URL

      http://www.u-tokyo-rad.jp/works/index.html

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Published: 2013-07-31   Modified: 2015-12-16  

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