2011 Fiscal Year Final Research Report
Improvement of graft regeneration with partial congestion in living donor liver transplantation
| Project/Area Number |
22791269
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Digestive surgery
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| Research Institution | Gifu University |
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Principal Investigator |
KIMURA Masaki 岐阜大学, 医学部・附属病院, 助教 (20422727)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 生体肝移植 / うっ血肝 / 肝再生 |
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| Research Abstract |
Hepatic venous congestion after living donor liver transplantation can cause primary non function. We evaluated the effectiveness of granulocyte-colony stimulating factor(G-CSF) for regeneration of remnant liver with venous congestion after hepatectomy in the past. But we were distressed to be established the model of living donor partial liver transplantation between rats. There were no living rats after 40% weight graft after transplantation. We have been making a model of living donor whole liver transplantation with partial congestion between rats. And we prepare for living donor liver transplantation in porcine model.
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