2012 Fiscal Year Final Research Report
Functional analysis of novel proteins associated with muscleregeneration.
| Project/Area Number |
22791389
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Kumamoto University |
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Principal Investigator |
NAKAYAMA Yuki 熊本大学, 大学院・自然科学研究科, 准教授 (30332381)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 筋ジストロフィー / 筋再生 / マウス |
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| Research Abstract |
The aim of this study is to investigate the physiological functionof RAMP and Brinp3 whose expression is enhanced in skeletal muscles after injury. Toelucidate the function of RAMP and Brinp3, I tried a yeast two-hybrid screen to identifyits interacting partners. Furthermore, to elucidate the physiological function of RAMPin regenerating muscle, I produced the mice conditionally inactivated RAMP in skeletalmuscle.
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