2012 Fiscal Year Final Research Report
Social Modulation of Pain in High-sociality Rodents.
| Project/Area Number |
22791438
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Kochi University (2010, 2012)
Aichi Medical University (2011) |
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Principal Investigator |
OSAKO Yoji 高知大学, 教育研究部医療学系, 准教授 (40335922)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 痛み / 社会性 / パートナーロス / 情動 |
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| Research Abstract |
Prairie voles are high-sociality rodents, which form strong pair bonds. In this study, the voles were evaluated to verify whether social environment modulates pain cognition. Partner-lost male voles showed higher anxiety levels in novel environment, lower threshold for mechanical stimulation-induced withdrawal reflex, and exacerbation of formalin-induced nociceptive pain as compared to partner-keep males. These results suggest that social environment can modulate pain cognition through emotional changes.
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