2012 Fiscal Year Final Research Report
The development of pharmacological postconditioning in diabetes rats and the elucidation of the molecular mechanism
| Project/Area Number |
22791442
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Nagasaki University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 薬理学的ポストコンディショニング / 塩酸ファスジル / 糖尿病 |
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| Research Abstract |
Fasudil induces PostC against myocardial infarction via activation of m-KATP channels in the rat. Although hyperglycemia attenuates the PostC, high-dose fasudil can restorecardioprotection.
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