2012 Fiscal Year Final Research Report
Elucidation of the monoamine dynamics at the descending pain modulation system in the diabetic neuropathy model rat
| Project/Area Number |
22791451
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Osaka City University |
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Principal Investigator |
友晴 Tomoharu 大阪市立大学, 大学院・医学研究科, 講師 (70433307)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 糖尿病性神経障害 / 下行性疼痛抑制系 / 脳内モノアミン |
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| Research Abstract |
We investigated the correlation between NA release in the LC and efficacy of morphine, tramadol, and clomipramine in rats with diabetic mellitus (DM).In the morphine group, NA release in the LC was not significantly correlated with the pain threshold. In
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