2011 Fiscal Year Final Research Report
Implantation of autologous bone marrow cells into radiation-injured urinary bladders Regenerates functional urinary bladders
| Project/Area Number |
22791471
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Urology
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| Research Institution | Shinshu University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Keywords | 再生医療 / 膀胱 / 骨髄由来細胞 / 放射線照射療法 / 排尿障害 |
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| Research Abstract |
Implantation of bone marrow-derived cells into radiation-injured rat urinary bladders reconstructed smooth muscle layers and nerve fibers. Some of the implanted cells differentiated into smooth muscle or nerve cells. The cell-implanted urinary bladders recovered regular voiding intervals and low residual volume. Therefore, the implantation of bone marrow-derived cells would be treatments for radiotherapy-induced bladder dysfunction.
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