2012 Fiscal Year Final Research Report
Analysis of the development of spiral ganglion cells utilizingPC3-GFP knock-in mice
| Project/Area Number |
22791610
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Kumamoto University |
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Principal Investigator |
YAMADA Takao 熊本大学, 医学部附属病院, 医員 (90573593)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 耳科学 |
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| Research Abstract |
In order to elucidate the development mechanism of cochlear spiralganglion cells, we investigated the PC3 gene. PC3 gene was expressed at the spiral ganglioncells of heterozygous PC3-GFP knock-in mice. Spiral ganglion cells were decreased inhomozygous PC3-GFP knock-in mice. The results indicate that PC3 gene is involved in thedevelopment of spiral ganglion cells.
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