2011 Fiscal Year Final Research Report
Effect of hydrogen gas in the age-related macular degeneration
| Project/Area Number |
22791688
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Ophthalmology
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| Research Institution | Keio University |
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Principal Investigator |
KOTO Takashi 慶應義塾大学, 医学部, 助教 (60464814)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 加齢黄斑変性 / 酸化ストレス / 水素ガス |
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| Research Abstract |
Age-related macular degeneration(AMD) is one of the leading causes of blindness in the aged population. The choroidal neovascularization and the related exudative changes are the main findings of AMD. It has been believed to be caused by oxidative stress, however, there was no established preventive therapies. In this study, we explored the possibility to use hydrogen gas to suppress oxidative stress in the retina, using an animal model.
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