2012 Fiscal Year Final Research Report
Development of new treatment by neuropeptide administration to neonatal necrotizing enterocolitis
| Project/Area Number |
22791712
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Pediatric surgery
|
|---|
| Research Institution | Kyoto Prefectural University of Medicine |
|---|
Principal Investigator |
SAKAI Kohei 京都府立医科大学, 医学部附属病院 小児外科, 専攻医 (30515292)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Keywords | 壊死性腸炎 / モデルラット / 神経ペプチド / ボンベシン / サイトカイン |
|---|
| Research Abstract |
Using the Sprague-Dawley rat fetuses, we was carried out to create NEC(necrotizing enterocolitis) model. We gave high concentration meal, hypoxia, oral administration of LPS(lipopolysaccharide). We succeed to creating of NEC model although, control of incidence rate was difficult, and bogged the survival.
|
