2012 Fiscal Year Final Research Report
The relationship between plasma free DNA and the mortality and morbidity of ICU patients.
Project/Area Number |
22791748
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Emergency medicine
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Research Institution | Kobe University |
Principal Investigator |
AOYAMA Michiko 神戸大学, 大学院・保健学研究科, 保健学研究員 (40566121)
|
Project Period (FY) |
2010 – 2012
|
Keywords | 外傷外科学 |
Research Abstract |
The plasma DNA concentration has been known to increase in the circulation of patients after trauma and may have prognostic potential. We examined the relevance of the plasma DNA concentration in ICU patients and their mortality. The average of plasma DNA concentrations for 3 days was higher, the mortality tended to be high in sepsis (p=0.08). In the non-septic patients, the plasma DNA concentrations of non-survived patients were higher than that of survived patients (p
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