• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2011 Fiscal Year Final Research Report

Gene expression of Cancer Stem Cell in Oral Squamous Cell Carcinoma

Research Project

  • PDF
Project/Area Number 22791777
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Morphological basic dentistry
Research InstitutionShowa University

Principal Investigator

ISOBE Tomohide  昭和大学, 歯学部, 助教 (40515855)

Project Period (FY) 2010 – 2011
Keywords口腔病理学
Research Abstract

Cancer stem cells can be the source of all the malignant cells in a primary tumor, they can compose the small reservoir of drug-resistant cells that are responsible for relapse after a chemotherapy induced remission. In this study, we isolated oral cancer stem cell-like cells and the gene expression profile of oral cancer stem cell-like cells was examined. Our results demonstrate that the expression of keratin 34 could be a useful marker for pathologic diagnosis in terms of predicting malignant change and be a one of the makers for OSCC cancer stem cell.

  • Research Products

    (5 results)

All 2011 2010

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (3 results)

  • [Journal Article] Sclerosing odontogenic carcinoma2011

    • Author(s)
      Irie Tarou、Tomohide Isobe
    • Journal Title

      Pathology International

      Volume: 62巻 Pages: 75-76

    • Peer Reviewed
  • [Journal Article] 口腔粘膜前癌病変のプロミクス解析口腔粘膜前癌病変の診断における新たな「尺度」を求めて2010

    • Author(s)
      入江太朗、磯邊友秀、立川哲彦
    • Journal Title

      日本病理学会

      Volume: 99巻1号 Pages: 387

    • Peer Reviewed
  • [Presentation] Identiffication of cancer stem cell-like fractions in OSCC and expression of CK15 as a putative cancer stem cell marker2010

    • Author(s)
      磯邊友秀
    • Organizer
      第69回日本癌学会総会
    • Place of Presentation
      大阪
    • Year and Date
      20100900
  • [Presentation] Identification of cancer stem cell-like fractions in cultured oral squamous cell carcinoma and expression of keratin15 as aputative cancer stem cell marker2010

    • Author(s)
      磯邊友秀
    • Organizer
      第19回日本癌転移学会学術集会・総会
    • Place of Presentation
      金沢
    • Year and Date
      20100600
  • [Presentation] Identification of cancer stem cell-like fractions in cultured oral squamous cell carcinoma and expression of keratin15 as aputative cancer stem cell marker2010

    • Author(s)
      Tomohide Isobe
    • Organizer
      AACR101st
    • Place of Presentation
      Washington DC
    • Year and Date
      20100400

URL: 

Published: 2013-07-31  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi