2011 Fiscal Year Final Research Report
Function of the basal cells of taste buds during taste bud development
| Project/Area Number |
22791793
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Functional basic dentistry
|
|---|
| Research Institution | Kagoshima University |
|---|
Principal Investigator |
NAKAYAMA Ayumi 鹿児島大学, 医歯学総合研究科, 助教 (10398290)
|
|---|
| Project Period (FY) |
2010 – 2011
|
| Keywords | 味覚 / 味蕾 / 細胞分化 / 発生 / 転写制御因子 / マウス |
|---|
| Research Abstract |
The relationship between the basal cell markers and Sox2, and timing of the basal cell marker appearance during development of the circumvallate papillae were analyzed. The results suggest that : 1) the beginning of taste bud development may be indicated by Prox1 expression before the expression of Shh and/or Sox2 is focused to taste bud primordia, 2) during the CV development, the onset of the basal cell marker expression in the apical epithelium precedes that in the trench wall.
|
