2011 Fiscal Year Final Research Report
Interaction between inflammatory cytokine and plasmin-induced COX-2 pathways in human dental pulp
| Project/Area Number |
22791846
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Conservative dentistry
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| Research Institution | Nihon University |
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Principal Investigator |
KAMIO Naoto 日本大学, 松戸歯学部, 助手 (10508774)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 歯学 / 細胞・組織 / 炎症 / プラスミン / シグナル伝達 |
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| Research Abstract |
This study clarifies interaction between inflammatory cytokine and plasmin-induced COX-2 pathways in human dental pulp cells. As a result, plasmin provoked COX-2 production via Ca/calcineurin/NFAT pathways. However, inflammatory cytokine had little or no effect on COX-2 mRNA expression by plasmin.
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Research Products
(6 results)
