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2012 Fiscal Year Final Research Report

Effects of mechanical stress on the differentiation into hard tissue formation cells from dental pulp cells

Research Project

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Project/Area Number 22791851
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Conservative dentistry
Research InstitutionTsurumi University

Principal Investigator

SHIRAKAWA Satoshi  鶴見大学, 歯学部, 助教 (50460176)

Project Period (FY) 2010 – 2012
Keywords歯内療法学 / メカニカルストレス
Research Abstract

The alkaline phosphatase activity, that shows the differentiation into hard tissue formation cells, on RPC-C2A cells was suppressed by mechanical stress. Also, alkaline phosphatase activity on human dental pulp cells was similarly suppressed by mechanical stress. These results show mechanical stress may suppress hard tissue formation cell.

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Published: 2014-08-29  

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