2011 Fiscal Year Final Research Report
Measurement of pressure distribution using tactile sensor and observation of bone metabolic activity using NaF-PET/CT under denture base in vivo
| Project/Area Number |
22791865
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Keywords | 義歯床下圧力動態 / 生体内測定 / NaF-PET / 骨代謝定量 / ヒト |
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| Research Abstract |
To examine how denture insertion influenced the bone metabolism at the residual ridge beneath the denture, Fluorine-18 NaF positron-emission tomography (PET)and computed tomography (CT)images were taken at baseline, 4-6 weeks, and 13 weeks after the denture use. Although CT value at bone beneath denture did not change, PET standardized uptake value increased during the 4-6 weeks after the denture insertion and then decreased despite no clinical complications in the denture-supporting tissues. This result indicates that wearing of a well adapted denture initially increases bone metabolism beneath the denture and then decreased at around 13 weeks after the denture use without bone structural change which clinical X-ray can detect.
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