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2011 Fiscal Year Final Research Report

Development of Cementum/PDL complex using human neural crest derived stem cells from PDL.

Research Project

  • PDF
Project/Area Number 22791875
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Prosthetic dentistry
Research InstitutionNiigata University

Principal Investigator

KAKU Masaru  新潟大学, 医歯学総合病院, 講師 (30547542)

Project Period (FY) 2010 – 2011
Keywords神経堤幹細胞 / 間葉系幹細胞 / 歯根膜
Research Abstract

The purpose of this study was to characterize the neural crest(NC) derived cells in adult periodontal ligament by using NC-traceable transgenic mice. Our study reveled that the distribution and prevalence of NC derived cells in adult PDL. Furthermore, the distribution of NC stem cell marker and mesenchymal stem cell marker positive cells were distinct.

  • Research Products

    (14 results)

All 2012 2011 2010

All Journal Article (2 results) Presentation (12 results)

  • [Journal Article] Identification and Characterization of Neural Crest-derived Cells in Adult Periodontal Ligament of Mice2012

    • Author(s)
      Kaku M, Komatsu Y, Mochida Y, Yamauchi M, Mishina Y, Ko CC
    • Journal Title

      Arch Oral Biol

      Volume: (in press)

  • [Journal Article] Analysis of patients visiting Niigata Medical and Dental Hospital with chief complaints of dental metal allergy and/or dental focal infection in the previous 8 years2011

    • Author(s)
      Akiba Y, Tomizuka K, Kaku M, Kawasaki M, Nagasawa M, Takano R, Uoshima K
    • Journal Title

      The Indonesian Journal of Dental Research

      Volume: 1(2)(in press)

  • [Presentation] Localization of Type XII Collagen and Its Interacting Molecules in PDL at Normal and Hyper Occlusal Condition2011

    • Author(s)
      Kaku M, Nozawa M, Rocavado JM Rosales, Uoshima K
    • Organizer
      The 7^<th> Biennial Meeting of Asian Academy of Prosthodontics
    • Place of Presentation
      Shanghai, China
    • Year and Date
      20111028-30
  • [Presentation] Gene expression of HSP27 During the course of osteoblast differentiation and mineralization2011

    • Author(s)
      Nozawa M, Kaku M, Rocavado JM Rosales, Uoshima K
    • Organizer
      The 7^<th> Biennial Meeting of Asian Academy of Prothodontics
    • Place of Presentation
      Shanghai, China
    • Year and Date
      20111028-30
  • [Presentation] Osteoblastic Differentiation and Mineralization Ability of Periosteum Derived Cells in vitro2011

    • Author(s)
      Rocavado JM Rosales, Kaku M, Nozawa M, Akiba Y, Uoshima K
    • Organizer
      新潟歯学会第2回例会
    • Place of Presentation
      新潟
    • Year and Date
      2011-11-12
  • [Presentation] 骨芽細胞分化過程におけるSmall Heat Shock Proteinの発現2011

    • Author(s)
      野澤恩美,加来賢, Rocavado JM Rosales,魚島勝美
    • Organizer
      第120回日本補綴歯科学会
    • Place of Presentation
      広島
    • Year and Date
      2011-05-21
  • [Presentation] 歯根膜におけるXII型コラーゲンの局在と石灰化能への影響2011

    • Author(s)
      加来賢, Rocavado JM Rosales,野澤恩美,魚島勝美
    • Organizer
      第120回日本補綴歯科学会
    • Place of Presentation
      広島
    • Year and Date
      2011-05-20
  • [Presentation] COL12A1 Gene Silencing Enhances Osteoblastic Differentiation of Human PDL Cells2011

    • Author(s)
      Kaku M., Rosales JM., Akiba Y., Nozawa M., Uoshima K.
    • Organizer
      IADR/AADR 89th General Session
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-03-16
  • [Presentation] Type XII Collagen Modulates Matrix Formation and Mineralization on Human PDL Cells2010

    • Author(s)
      Kaku M., Rosales JM., Akiba Y., Nozawa M., Uoshima K.
    • Organizer
      International Joint Symposium on Oral Science
    • Place of Presentation
      Bali, INDONESIA
    • Year and Date
      2010-12-17
  • [Presentation] Mechanical Loading Induces the MMP-13 induction at Epithelial Rests of Malassez2010

    • Author(s)
      Kawasaki M, Kaku M, Rocavado JM Rosales, Nozawa M, Uoshima K.
    • Organizer
      International Joint Symposium on Oral Science
    • Place of Presentation
      Bali, INDONESIA
    • Year and Date
      2010-12-17
  • [Presentation] Hyper-Occlusal Loading Affects to the Expression of Collagen Modifying Enzymes2010

    • Author(s)
      Kaku M., Kawasaki M., Rosales JM., Uoshima K.
    • Organizer
      JADR 58th General Session
    • Place of Presentation
      北九州
    • Year and Date
      2010-11-20
  • [Presentation] Effect of Mechanical Loading on Post-translational Modifications of Collagen2010

    • Author(s)
      Kaku M., Kawasaki M., Rocavado JM Rosales., Uoshima K.
    • Organizer
      IADR/AADR 88th General Session
    • Place of Presentation
      Barcelona, SPAIN
    • Year and Date
      2010-07-15
  • [Presentation] Effect of HDACIs on mesenchymal stem cell in osteogenic differentiation2010

    • Author(s)
      Akiba Y., Kaku M., Nagasawa M., Bhuiyan A., Uoshima K.
    • Organizer
      IADR/AADR 88th General Session
    • Place of Presentation
      Barcelona, SPAIN
    • Year and Date
      2010-07-15
  • [Presentation] Detection of MMP-13 among Dental Follicle Cells during tooth eruption.2010

    • Author(s)
      Kawasaki M., Kaku M., Rashid Md. M., Uoshima K.
    • Organizer
      IADR/AADR 88th General Session
    • Place of Presentation
      Barcelona, SPAIN
    • Year and Date
      2010-07-15

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Published: 2013-07-31   Modified: 2014-09-10  

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