2011 Fiscal Year Final Research Report
The Relationship between Sleep Bruxism and Peripheral-type Benzoidiazepine Receptor Gene Polymorphism
| Project/Area Number |
22791898
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Fukuoka Dental College (2011)
Kyushu Dental College (2010) |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Keywords | ブラシキズム / ストレス / 遺伝子多型 |
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| Research Abstract |
The objective of this study is to clarify the relationship between sleep bruxism behavior and Chromogranin A(CgA) level in saliva and Peripheral-type Benzodiazepine Receptor(PBR) gene polymorphism. We used small electromyographic monitors for measuring sleep bruxism. We measured the concentration of CgA in saliva as a stress biomarker. We analyzed PBR gene and administered the StateTrait Anxiety Inventory(STAI) to the subjects. The groups of the polymorphism of the PBR gene were significantly correlated with the number of bruxism event. We suggested that the subjects of the polymorphism PBR gene might have a higher risk of Sleep bruxism.
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