2011 Fiscal Year Final Research Report
Bone regeneration using autologous fibrin gel with adipose derived stem cells
| Project/Area Number |
22791930
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Nagasaki University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
|
| Keywords | 脂肪由来幹細胞 / フィブリン / 骨再生 / PRF / インプラント |
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| Research Abstract |
Adipose derived stem cells(ADSCs), which have high proliferation potency and pluripotency, can be extracted from adipose tissue. The purpose of this study was to develop a bone regeneration using ADSCs and fibrin gel. When ADSCs were cultured in osteogenic medium without BMP-2, differentiation of ADSCs into osteoblastic cells was not sufficient. On the other hand, bone regeneration was seen when autologous fibrin gel was grafted into a closed cavity such as sinus making a space for bone regeneration.
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