2012 Fiscal Year Final Research Report
Bone regeneration by layered osteoblast cell sheets - rhBMP
| Project/Area Number |
22791945
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Aichi Gakuin University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Keywords | 再生歯学 |
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| Research Abstract |
The aim of this study is to promote bone defect healing by layered osteoblast cell sheets implantation. First of all, temperature-responsive culture dishes were used to obtain cell sheets of rat osteoblast cells (v-1 cell). However, only partial cell sheets were obtained. Furthermore, it was quite difficult to make layered osteoblast cell sheets using these partial cell sheets. These results suggest that it depends on the type of cell cultured whether cell the sheet was successfully obtained or not.
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