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2012 Fiscal Year Final Research Report

Study of anti-tumor effect and creation of osteonecrosis of the jaw model mice by bone resorption inhibitor bisphosphonates

Research Project

  • PDF
Project/Area Number 22791949
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Surgical dentistry
Research InstitutionTohoku University

Principal Investigator

OIZUMI Takefumi  東北大学, 病院, 医員 (40547262)

Project Period (FY) 2010 – 2012
Keywords顎骨壊死 / ビスホスホネート
Research Abstract

Results of this study, in vitro effects of a nitrogen-containing bisphosphonate (NBP) (zoledronate) and a non-NBP(etidronate), alone or in combination, on periodontal and other cells. For the preparation of osteonecrosis of the jawbone model mice, I wasconsidered created difficult in mice jawbone.

  • Research Products

    (6 results)

All 2013 2012 2011

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (5 results)

  • [Journal Article] In vitro cytotoxicity of zoledronate (nitrogen-containing bisphosphonate: NBP) and/or etidronate (non-NBP) in tumourcells and periodontal cells2013

    • Author(s)
      Takefumi Oizumi
    • Journal Title

      Arch Oral Biol

      Volume: 58(6) Pages: 628-37

    • DOI

      doi:10.1016/j.archoralbio.2012.11.010

    • Peer Reviewed
  • [Presentation] 当科におけるビスフォスフォネート投与患者の状況2012

    • Author(s)
      大泉丈史
    • Organizer
      第57回日本口腔外科学会
    • Place of Presentation
      横浜
    • Year and Date
      2012-10-20
  • [Presentation] 窒素含有bisphosphonates(NBPs)による顎骨壊死:non-NBPのetidronate(ダイドロネル)への切り換えを試みた5症例2012

    • Author(s)
      大泉丈史
    • Organizer
      第14回日本骨粗鬆症学会
    • Place of Presentation
      新潟
    • Year and Date
      2012-09-27
  • [Presentation] 窒素含有bisphosphonates(NBPs)による顎骨壊死:non-NBPのetidronate(ダイドロネル)への切り換えを試みた5症例2012

    • Author(s)
      大泉丈史
    • Organizer
      第33回東北骨代謝研究会
    • Place of Presentation
      仙台
    • Year and Date
      2012-02-04
  • [Presentation] ヒト・マウスの種々の細胞 におよぼす zoledronate とetidronate の in vitroでの効果In vitro effects of zoledronate and etidronate on various human and murine cells2011

    • Author(s)
      大泉丈史
    • Organizer
      第53回歯科基礎医学会
    • Place of Presentation
      岐阜
    • Year and Date
      2011-09-30
  • [Presentation] BRONJに対する窒素非含有ビスフォスフォネートへの切り換えの試み2011

    • Author(s)
      大泉丈史
    • Organizer
      第56回日本口腔外科学会
    • Place of Presentation
      大阪
    • Year and Date
      2011-09-10

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Published: 2014-08-29  

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