2012 Fiscal Year Final Research Report
The Bone Regenerative effect of Osteoblasts on Novel Hydroxyapatite Ceramics
| Project/Area Number |
22791981
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | Hiroshima University |
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Principal Investigator |
TADA Misato (HIRAOKA Misato) 広島大学, 病院, 歯科診療医 (40572326)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 多孔質セラミックス / ハイドロキシアパタイト / ヒト骨芽細胞 / 骨再生 / IP-CHA |
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| Research Abstract |
IP-CHA(Interconnected Porous Calcium Hydroxyapatite)is an excellent ceramic for use in bone tissue engineering because of its fully interconnected porous structure, which allows osteoblasts dispersion and supports their osteogenic differentiation. This study provided biochemical evidence that the IP-CHA/osteoblasts composite and IP-CHA / osteoblasts / TGF-β1 (Transforming growth factor-・1)composite could enhance osteogenic potential. It was strongly suggested that IP-CHA was a useful biomaterial for bone tissue regeneration.
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[Journal Article] 3-dimensional composite scaffolds consisting of apatite-PLGAatelocollagen for bone tissue engineering2012
Author(s)
Takechi M, Ohta K, Ninomiya Y, Tada M, Minami M, Takamoto M, Ohta A, Nakagawa T, Fukui A, Miyamoto Y, Kamata N.
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Journal Title
Dent Mater J
Volume: 31(3)
Pages: 465-71
Peer Reviewed
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[Presentation] 炭酸アパタイト-PLGA複合体による新規骨再生材料の開発2011
Author(s)
太田 彰,武知正晃, 太田耕司,二宮嘉昭,中川貴之,多田美里,南 正彦,高本 愛,都留寛治,石川邦夫,鎌田伸之
Organizer
第33回日本バイオマテリアル学会総会
Place of Presentation
京都
Year and Date
2011-11-22
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[Presentation] Fabrication and basic properties of poly(DL-lactide-co-glycolide) containing Carbonated apatite2011
Author(s)
Ota A, Takechi M, Ota K, Ninomiya Y, Nakagawa T, Tada M, Minami M, Takamoto M, Tsuru K, Ishikawa K, Kamata N
Organizer
4th Hiroshima Conference on Education and Science in Dentistry
Place of Presentation
広島
Year and Date
2011-10-10
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