2011 Fiscal Year Final Research Report
The elucidation of the new osteoclast differentiation factor revealed from the pressure zone of periodontal ligament cells during tooth movement
| Project/Area Number |
22792072
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Tsurumi University |
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Principal Investigator |
ARAI Chihiro 鶴見大学, 歯学部, 助教 (10460221)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 歯科矯正学 / 歯の移動 / Heat Shock Protein |
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| Research Abstract |
Gene expression of the pressure zone of periodontal ligament cells(PDL) during orthodontic tooth movement in vivo was observed. Heat shock protein A1A(HSPA1A) in the pressure zone of the PDL was higher during 6 h of tooth movement than that in the control group. These results strongly suggest that expression of HSPA1A in the PDL during the early stage of tooth movement is a critical factor for tissue reaction.
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