2011 Fiscal Year Final Research Report
The function of miRNA in postnatal development of the muscle of mastication and gustro of the third molar deficit model mouse
| Project/Area Number |
22792073
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Tsurumi University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Keywords | ELマウス / 第三臼歯欠損 / シナプス形成 / miRNA / ミオシン重鎖 / 咬筋 |
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| Research Abstract |
The results using mutant mice with deficiency of the 3^<rd> molars suggest that normal occlusal activity is essential for synaptogenesis in the masseter muscle. The results using wild type mice suggest that miRNA-1 regulates the expression of myosin heavy chains in the masseter muscle.
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Research Products
(3 results)
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[Journal Article] Effect of third molar absence on development of masticatory muscles in EL mice2010
Author(s)
NARIYAMA, M., KOTA, Y., TASHIMA, I., TOMOHIRO, T., YAMANE, A. and ASADA, Y
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Journal Title
Pediatric Dent. J
Volume: 20(2)
Pages: 122-129
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