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2011 Fiscal Year Final Research Report

The function of miRNA in postnatal development of the muscle of mastication and gustro of the third molar deficit model mouse

Research Project

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Project/Area Number 22792073
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Orthodontic/Pediatric dentistry
Research InstitutionTsurumi University

Principal Investigator

TOMOHIRO Tadafumi  鶴見大学, 歯学部, 臨床助手 (30460231)

Project Period (FY) 2010 – 2011
KeywordsELマウス / 第三臼歯欠損 / シナプス形成 / miRNA / ミオシン重鎖 / 咬筋
Research Abstract

The results using mutant mice with deficiency of the 3^<rd> molars suggest that normal occlusal activity is essential for synaptogenesis in the masseter muscle. The results using wild type mice suggest that miRNA-1 regulates the expression of myosin heavy chains in the masseter muscle.

  • Research Products

    (3 results)

All 2010

All Journal Article (1 results) Presentation (2 results)

  • [Journal Article] Effect of third molar absence on development of masticatory muscles in EL mice2010

    • Author(s)
      NARIYAMA, M., KOTA, Y., TASHIMA, I., TOMOHIRO, T., YAMANE, A. and ASADA, Y
    • Journal Title

      Pediatric Dent. J

      Volume: 20(2) Pages: 122-129

  • [Presentation] Effects of lack of cclusal activity on masticatory myogenesis2010

    • Author(s)
      NARIYAMA, M., KOTA, Y., YAMANE, A., TOMOHIRO, T. and ASADA, Y
    • Organizer
      88th General Session & Exhibition of the IADR. Centre de Convencions Internacional Barcelona
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      20100714-17
  • [Presentation] マウス第三臼歯欠如が咀嚼筋の発達過程に及ぼす影響2010

    • Author(s)
      成山明具美、古宇田ゆき、田島格、友廣忠文、山根明、朝田芳信
    • Organizer
      第48回小児歯科学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      20100519-20

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Published: 2013-07-31  

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