2011 Fiscal Year Final Research Report
Examination of pathogenesis of periodontal disease through ascorbic acid transporter SVCTs
| Project/Area Number |
22792099
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Periodontal dentistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
IWASAKI Kengo 東京医科歯科大学, 大学院・医歯学総合研究科, 寄附講座教員 (40401351)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 幹細胞 / アスコルビン酸代謝 / 歯根膜 |
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| Research Abstract |
Ascorbic acid is water-soluble vitamin which has important role in collagen metabolism. This study revealed that SVCTs, ascorbic acid transporter, expressed widely in collagen-rich connective tissue, periodontal ligament. This result suggests that SVCT may contribute to keeping of homeostasis of periodontal tissues and to pathogenesis of periodontal disease.
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