2012 Fiscal Year Final Research Report
Elucidation of mechanism of developing the periodontitis at the host-parasite interface
| Project/Area Number |
22792104
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Social dentistry
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| Research Institution | Tohoku University |
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Principal Investigator |
MAYANAGI Gen 東北大学, 大学院・歯学研究科, 助教 (10451600)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 細菌学 / 免疫学 / 遺伝学 / 歯周病学 |
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| Research Abstract |
Analyzing the subgingival plaque and the gingival tissues samples, it was elucidated that the deeper the periodontal pocket the patient has, the larger the amounts of the anaerobic bacteria and the inflammatory cytokines were detected. It is possible to evaluate the profiles of the clinical conditions of periodontitis in the initial preparation stage from the views of microbiology and immunology. In the future, we will be able to provide the effective treatment for the periodontitis patient by profiling the amounts of the anaerobic bacteria and the inflammatory cytokines.
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