A study of effective treatment for extravasation

2015 Fiscal Year Final Research Report

• Project/Area Number: 22792152
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Fundamental nursing
• Research Institution: Iwate Prefectural University
• Principal Investigator: Miura Natsuko (小山奈都子) 岩手県立大学, 看護学部, 講師 (40347191)
• Project Period (FY): 2010-04-01 – 2016-03-31
• Keywords: 抗がん剤 / 血管外漏出 / 点滴漏れ / 静脈注射 / 罨法 / ステロイド局所注射

Outline of Final Research Achievements

It is often the case that a drug administered by infusion leak out into the skin tissues outside the blood vessels and cause damage to the skin tissues.As care for drip leakage, hot packs, cold packs, or application of steroid ointment has been carried out. Moreover, local injection of steroids has been performed for extravasation of anticancer agents. The purpose of this study was to examine the effectiveness of these types of care.
After injecting drug solution into the dorsal skin of mice, we performed each treatment. The results showed that cold packs at about at 20 ℃ and application of steroid ointment significantly reduced the area of swelling. In addition, redness was not observed in the case of application of steroid ointment.Damage was likely to be increased when steroid was locally injected for the leakage of anticancer agents; thus, necrosis formation was not prevented.

Free Research Field

基礎看護学