2011 Fiscal Year Final Research Report
The antitumor effects of nerve growth factor on human cancer cells
| Project/Area Number |
22800045
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied health science
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| Research Institution | Okayama University |
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Principal Investigator |
TAKATORI Shingo 岡山大学, 大学院・医歯薬学総合研究科, 助教 (20368707)
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| Co-Investigator(Renkei-kenkyūsha) |
KAWASAKI Hiromu 岡山大学, 大学院・医歯薬学総合研究科, 教授 (60125151)
HASHIKAWA Narumi (HOBARA Narumi) 岡山理科大学, 理学部・臨床生命科学科, 講師 (30511159)
GODA Mitsuhiro 新潟大学, 大学院・医歯学総合研究科, 助教 (40585965)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 神経成長・栄養因子 / Nerve growth factor / がん新生血管 / 血管周囲神経 / 抗腫瘍効果 |
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| Research Abstract |
Our present study demonstrated new findings that NGF markedly suppressed the growth of hepatic tumor cell(HepG2) and fibrosarcoma cell(HT1080) via the indirect effect, probably innervation or maturation of tumor neovasculature.
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