2011 Fiscal Year Final Research Report
Association of Vitamin D status with upper respiratory tract infection and all-cause mortality in the Japanese institutionalized elderly
| Project/Area Number |
22800072
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Osaka Shoin Women's University |
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Principal Investigator |
KUWABARA Akiko 大阪樟蔭女子大学, 学芸学部・健康栄養学科, 講師 (00582602)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 栄養学 / 臨床 |
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| Research Abstract |
We have performed a prospective 2-year cohort study for 208 Japanese institutionalized elderly to study the risk factors for all-cause mortality and upper tract respiratory infection with emphasis on serum vitamin D level and BMI. Vitamin D deficiency(25OHD<10ng/mL) was associated with increased infection, although not statistically significant by Kaplan. Meier plots(log-rank test ; p=0.20). Serum vitamin D level was not significantly associated with all-cause mortality or upper respiratory tract infection by Cox regression analyses. BMI was a significant predictor for all-cause mortality(HR, 0.86, 95% CI ; 0.76-0.97) by Cox regression analyses. BMI. 20.3 kg/m2 was associated with significantly increased risk of mortality.
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