2011 Fiscal Year Final Research Report
Monitoring of cellular response to applied mechanical stimulus in bone cells by infrared spectroscopy
| Project/Area Number |
22860002
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Materials/Mechanics of materials
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| Research Institution | Tohoku University |
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Principal Investigator |
AONUMA Yuki 東北大学, 電気通信研究所, 助教 (80582262)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 細胞情報・動態 / 骨芽細胞 / 赤外分光 |
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| Research Abstract |
This study has aimed to apply infrared spectroscopy as a label free and real-time monitoring method for detecting cellular response to applied mechanical stimulus in bone cells. Infrared light penetrated through semiconductor prism was probed activity of adhesive cells on the prism as infrared absorption. In addition, live cell monitoring apparatus was fabricated for detecting kinetic information of target cells, which was applicable to experimental system to apply fluid flow stimulation.
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