2011 Fiscal Year Final Research Report
Effect of continuous dietary supplementation with EGCG on suppression of postprandial hyperglycemia via regulation of small intestinal function
| Project/Area Number |
22880028
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Food science
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| Research Institution | Chiba Prefectural University of Health Sciences |
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Principal Investigator |
SHIMADA Masaya 千葉県立保健医療大学, 健康科学部, 助教 (10576755)
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| Project Period (FY) |
2010 – 2011
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| Keywords | EGCG / α-グルコシダーゼ / GIP / 小腸 / 食後高血糖 |
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| Research Abstract |
I found that continuously feeding rats a diet containing EGCG reduces GIP protein level as well as alpha-glucosidase activities in the upper small intestine. These suggest that the reductions of the alpha-glucosidase activities and GIP protein level may lead to suppressions of postprandial hyperglycemia and hyperinsulinemia via regulation of small intestinal function.
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