2011 Fiscal Year Final Research Report
In Vivo Evaluation of Deep Structure of Optic Disc in Glaucoma Using Swept Source Optical Coherence Tomography
| Project/Area Number |
22890097
|
|---|
| Research Category |
Grant-in-Aid for Research Activity Start-up
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Ophthalmology
|
|---|
| Research Institution | Kyoto University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2010 – 2011
|
| Keywords | 緑内障 / 波長走査型光干渉断層計 / 視神経乳頭深部構造 |
|---|
| Research Abstract |
The lamina cribrosa of glaucoma eyes was proved to be more vertically W-shaped than that of normal eyes by using swept source optical coherence tomography, which indicated that deformation of the lamina causing the glaucomatous optic neuropathy could be observed in vivo. Furthermore, the eyes with temporal scleral protrusion showed visual field defects more than those without. The angle of the scleral protrusion of high myopic eyes was significantly correlated to the RNFL thickness above the protrusion and the visual field severity. These indicate that some of the high myopias are affected by direct scleral compression or stretching at peripapillary region. Deep structural changes in glaucoma and peripapillary scleral changes in high myopia are related to the optic nerve damage.
|
Research Products
(11 results)
-
-
[Journal Article] Association Between Hyperreflective Foci in the Outer Retina, Status of Photoreceptor Layer, and Visual Acuity in Diabetic Macular Edema2012
Author(s)
Uji A, Murakami T, Nishijima K, Akagi T, Horii T, Arakawa N, Muraoka Y, Ellabban AA, Yoshimura N
-
Journal Title
Am J Ophthalmol
Volume: 153(4)
Pages: 710-717
DOI
Peer Reviewed
-
-
-
-
-
[Presentation] Three-dimensional Reconstructed Imaging of Deep Structures of the Optic Disc by Optical Coherence Tomography Radial Sectioning2011
Author(s)
Akagi T, Hangai M, Nonaka A, Hanako O. Ikeda, Mori S, Nukada M, Nakano N, Takayama K, Morooka S, Yoshimura N
Organizer
The Association fo Research in Vision and Ophthalmology(ARVO)
Place of Presentation
Fort Lauderdale, USA
Year and Date
20110501-05
-
-
-
-
