2011 Fiscal Year Final Research Report
Therapeutic perspective of tumor microenvironment in non-small-cell lung cancer.
| Project/Area Number |
22890106
|
|---|
| Research Category |
Grant-in-Aid for Research Activity Start-up
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Thoracic surgery
|
|---|
| Research Institution | Osaka University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2010 – 2011
|
| Keywords | 肺癌 / 癌微小環境 |
|---|
| Research Abstract |
Our recent focus has been signaling pathways that promote Epithelial to mesenchymal transition(EMT) in response to tumor microenvironment such as growth factors as well as extracellular matrix. Tumor stroma in non-small cell lung cancer(NSCLC) is of interest in the entity as both biomarkers and therapy targets. We can assume that anticancer therapeutics targeting EMT pathways and signaling elements will bring additional ways for the treatment of NSCLC.
|
-
[Journal Article] Epithelial to mesenchymal transition is a determinant of sensitivity to chemoradiotherapy in non-small cell lung cancer2011
Author(s)
Shintani Y, Okimura A, Sato K, Nakagiri T, Kadota Y, Inoue M, Sawabata N, Minami M, Ikeda N, Kawahara K, Matsumoto T, Matsuura N, Ohta M, Okumura M
-
Journal Title
Ann Thorac Surg
Volume: 82
Pages: 1794-804
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
