2011 Fiscal Year Final Research Report
Creation of polyclonal antibody of secreted protein SEPINE2, which is expressed in testicular cancer cell line with high metastatic potential. How does it work in testicular cancer metastasis?
| Project/Area Number |
22890108
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Urology
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| Research Institution | Osaka University |
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Principal Investigator |
NAGAHARA Akira 大阪大学, 医学部附属病院, 医員 (90588774)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 精巣腫瘍 / 転移 / SERPINE2 |
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| Research Abstract |
We tried to create a polyclonal antibody of secreted protein SERPINE2 that we had reported before and to elucidate how it work in testicular cancer metastasis. Although we established stable SERPINE-expressed testicular cancer cell line, we couldn' t get evidence that SERPINE2 was metastatic promoter in vivo and mRNA expression analysis in clinical samples. And we regretted to create the antibody of SERPINE2.
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