2011 Fiscal Year Final Research Report
The effects of gene associated with sucrose phosphotransferase system on biofilm formation of Streptococcus mutans
| Project/Area Number |
22890123
|
|---|
| Research Category |
Grant-in-Aid for Research Activity Start-up
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Conservative dentistry
|
|---|
| Research Institution | The University of Tokushima |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2010 – 2011
|
| Keywords | 歯学 / う蝕 / 細菌 / 遺伝子 / バイオフィルム |
|---|
| Research Abstract |
The aim of this study was to investigate the relationship between scrA gene deeply related to the acidogenic activity in cariogenic bacterium, Streptococcus mutans, and biofilm formation. Scanning electron microscopic observation and real-time PCR analysis demonstrated that scrA gene affects the expression of various genes involved in the synthesis of glucan, a component of biofilm.
|
