2011 Fiscal Year Final Research Report
Gene expression analysis for neuronal cells differenciated from iPS cells generated from patients with Down syndrome
| Project/Area Number |
22890199
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Pediatrics
|
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| Research Institution | Tokyo Women's Medical University |
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Principal Investigator |
|
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| Project Period (FY) |
2010 – 2011
|
| Keywords | iPS細胞 / ダウン症候群 / 神経細胞機能解析 |
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| Research Abstract |
In this study, we generated disease specific iPS cells from the patients with Down syndrome. Gene expression analysis identified significant increases of some genes. This may be important clue to reveal neuronal impairments in Down syndrome.
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